Endocrine Abstracts

Promotion of angiogenesis, the formation of new blood vessel from preexisting blood vessels, is the focus of intense research and therapeutic efforts. In contrast, inhibition of endothelial cell growth and survival is a strategy to target many proliferative diseases. Various studies have shown that angiogenic growth factors are produced and secreted by normal endocrine cells and are increased in pathological states, including inflammation and hyperplasia. Importantly, angiogen...